New Paper in PLoS Pathogens

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Chlamydial elementary bodies have mostly been thought of as dormant, spore-like particles. However, Barbara Sixt, Alexander Siegl, Matthias Horn and colleagues now demonstrate metabolic activity in chlamydial elementary bodies that is linked to infectivity. Challenging textbook knowledge, these results suggest that the infective stage is much more dependent on its environment (and thus potentially vulnerable) than previously recognized.